SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR

Open Access

Peer-reviewed

Research Article

J. Terrig Thomas ,

* E-mail: john.thomas@fda.hhs.gov

Affiliation FDA/Center for Biologics Evaluation and Research, Division of Cellular and Gene Therapies Office of Cellular, Tissue, and Gene Therapies, Silver Spring, MD, United States of America
⨯
Lina Chhuy-Hy,

Affiliation FDA/Center for Biologics Evaluation and Research, Division of Cellular and Gene Therapies Office of Cellular, Tissue, and Gene Therapies, Silver Spring, MD, United States of America
⨯
Kristin R. Andrykovich,

Affiliation FDA/Center for Biologics Evaluation and Research, Division of Cellular and Gene Therapies Office of Cellular, Tissue, and Gene Therapies, Silver Spring, MD, United States of America
⨯
Malcolm Moos Jr.

Affiliation FDA/Center for Biologics Evaluation and Research, Division of Cellular and Gene Therapies Office of Cellular, Tissue, and Gene Therapies, Silver Spring, MD, United States of America
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MAPK signaling cascades
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BMP signaling
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ERK signaling cascade
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EGFR signaling
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Xenopus
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Recombinant proteins
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Membrane receptor signaling
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Signal inhibition
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