Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types

Fumiyasu Momose; Naohiro Seo; Yasushi Akahori; Shin-ichi Sawada; Naozumi Harada; Toru Ogura; Kazunari Akiyoshi; Hiroshi Shiku

doi:10.1371/journal.pone.0154134

Loading metrics

Open Access

Peer-reviewed

Research Article

Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types

Fumiyasu Momose,

Affiliations Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie 514–8507, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯
Naohiro Seo ,

* E-mail: seo-naohiro@clin.medic.mie-u.ac.jp (NS); shiku@clin.medic.mie-u.ac.jp (HS)

Affiliations Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie 514–8507, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯
Yasushi Akahori,

Affiliations Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie 514–8507, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯
Shin-ichi Sawada,

Affiliations Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615–8510, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯
Naozumi Harada,

Affiliations Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie 514–8507, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯
Toru Ogura,

Affiliation Clinical Research Support Center, Mie University Hospital, Tsu Mie 514–8507, Japan
⨯
Kazunari Akiyoshi,

Affiliations Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615–8510, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯
Hiroshi Shiku

* E-mail: seo-naohiro@clin.medic.mie-u.ac.jp (NS); shiku@clin.medic.mie-u.ac.jp (HS)

Affiliations Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie 514–8507, Japan, ERATO Bio-Nanotransporter Project, Japan Science and Technology Agency (JST), Tokyo 102–0076, Japan
⨯

Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types

Fumiyasu Momose,
Naohiro Seo,
Yasushi Akahori,
Shin-ichi Sawada,
Naozumi Harada,
Toru Ogura,
Kazunari Akiyoshi,
Hiroshi Shiku

Published: April 21, 2016
https://doi.org/10.1371/journal.pone.0154134

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Exosomes
Is the Subject Area "Exosomes" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Flow cytometry
Is the Subject Area "Flow cytometry" applicable to this article?

Thanks for your feedback.
Sequence motif analysis
Is the Subject Area "Sequence motif analysis" applicable to this article?

Thanks for your feedback.