A Digital PCR-Based Method for Efficient and Highly Specific Screening of Genome Edited Cells

Open Access

Peer-reviewed

Research Article

Scott D. Findlay ,

Contributed equally to this work with: Scott D. Findlay, Krista M. Vincent

Affiliations Department of Anatomy and Cell Biology, Faculty of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada, Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Krista M. Vincent ,

Contributed equally to this work with: Scott D. Findlay, Krista M. Vincent

Affiliations Department of Anatomy and Cell Biology, Faculty of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada, Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Jennifer R. Berman,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
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Lynne-Marie Postovit

* E-mail: postovit@ualberta.ca

Affiliation Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
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Cloning
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TALENs
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Genomics
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Polymerase chain reaction
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Non-homologous end joining
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Nucleases
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Mutation detection
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