Whole Exome Sequencing Reveals Homozygous Mutations in RAI1, OTOF, and SLC26A4 Genes Associated with Nonsyndromic Hearing Loss in Altaian Families (South Siberia)

Alexander Y. Сhurbanov; Tatiana M. Karafet; Igor V. Morozov; Valeriia Yu. Mikhalskaia; Marina V. Zytsar; Alexander A. Bondar; Olga L. Posukh

doi:10.1371/journal.pone.0153841

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Research Article

Whole Exome Sequencing Reveals Homozygous Mutations in RAI1, OTOF, and SLC26A4 Genes Associated with Nonsyndromic Hearing Loss in Altaian Families (South Siberia)

Alexander Y. Сhurbanov ,

Contributed equally to this work with: Alexander Y. Сhurbanov, Olga L. Posukh

Affiliation Arizona Research Laboratories, Division of Biotechnology, University of Arizona, Tucson, Arizona, United States of America
⨯
Tatiana M. Karafet,

Affiliation Arizona Research Laboratories, Division of Biotechnology, University of Arizona, Tucson, Arizona, United States of America
⨯
Igor V. Morozov,

Affiliations SB RAS Genomics Core Facility, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation, Novosibirsk State University, Novosibirsk, Russian Federation
⨯
Valeriia Yu. Mikhalskaia,

Affiliations Novosibirsk State University, Novosibirsk, Russian Federation, Laboratory of Human Molecular Genetics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
⨯
Marina V. Zytsar,

Affiliations Novosibirsk State University, Novosibirsk, Russian Federation, Laboratory of Human Molecular Genetics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
⨯
Alexander A. Bondar,

Affiliation SB RAS Genomics Core Facility, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
⨯
Olga L. Posukh

Contributed equally to this work with: Alexander Y. Сhurbanov, Olga L. Posukh

* E-mail: posukh@bionet.nsc.ru

Affiliations Novosibirsk State University, Novosibirsk, Russian Federation, Laboratory of Human Molecular Genetics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation

http://orcid.org/0000-0003-1352-3591

⨯

Whole Exome Sequencing Reveals Homozygous Mutations in RAI1, OTOF, and SLC26A4 Genes Associated with Nonsyndromic Hearing Loss in Altaian Families (South Siberia)

Alexander Y. Сhurbanov,
Tatiana M. Karafet,
Igor V. Morozov,
Valeriia Yu. Mikhalskaia,
Marina V. Zytsar,
Alexander A. Bondar,
Olga L. Posukh

Published: April 15, 2016
https://doi.org/10.1371/journal.pone.0153841

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