Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources

Ravi Shah; Kahraman Tanriverdi; Daniel Levy; Martin Larson; Mark Gerstein; Eric Mick; Joel Rozowsky; Robert Kitchen; Venkatesh Murthy; Ekaterina Mikalev; Jane E. Freedman

doi:10.1371/journal.pone.0153691

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Open Access

Peer-reviewed

Research Article

Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources

Ravi Shah ,

Contributed equally to this work with: Ravi Shah, Kahraman Tanriverdi

Affiliation Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA, 02215, United States of America
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Kahraman Tanriverdi ,

Contributed equally to this work with: Ravi Shah, Kahraman Tanriverdi

Affiliation University of Massachusetts Medical School, Department of Medicine, Division of Cardiovascular Medicine, Worcester, MA, 01605, United States of America
⨯
Daniel Levy,

Affiliation The Framingham Heart Study, Framingham, MA, United States of America and Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States of America
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Martin Larson,

Affiliation The Framingham Heart Study, Framingham, MA, United States of America and Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States of America
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Mark Gerstein,

Affiliation Yale University Medical School, Computational Biology & Bioinformatics Program, New Haven, CT, 06520, United States of America
⨯
Eric Mick,

Affiliation University of Massachusetts Medical School, Department of Quantitative Health Sciences, Worcester, MA, 01605, United States of America
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Joel Rozowsky,

Affiliation Yale University Medical School, Computational Biology & Bioinformatics Program, New Haven, CT, 06520, United States of America
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Robert Kitchen,

Affiliation Yale University Medical School, Computational Biology & Bioinformatics Program, New Haven, CT, 06520, United States of America
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Venkatesh Murthy,

Affiliation Department of Cardiology, University of Michigan, Ann Arbor, Michigan, 1500 E. Medical Center Dr. SPC 5873, Ann Arbor, MI, 48109, United States of America
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Ekaterina Mikalev,

Affiliation University of Massachusetts Medical School, Department of Medicine, Division of Cardiovascular Medicine, Worcester, MA, 01605, United States of America
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Jane E. Freedman

* E-mail: jane.freedman@umassmed.edu

Affiliation University of Massachusetts Medical School, Department of Medicine, Division of Cardiovascular Medicine, Worcester, MA, 01605, United States of America
⨯

Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources

Ravi Shah,
Kahraman Tanriverdi,
Daniel Levy,
Martin Larson,
Mark Gerstein,
Eric Mick,
Joel Rozowsky,
Robert Kitchen,
Venkatesh Murthy,
Ekaterina Mikalev

Published: April 28, 2016
https://doi.org/10.1371/journal.pone.0153691

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Blood plasma
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Blood
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RNA isolation
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RNA sequencing
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Plasma proteins
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