Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression

Jérémie D. Goldstein; Aude Burlion; Bruno Zaragoza; Kélhia Sendeyo; Julia K. Polansky; Jochen Huehn; Eliane Piaggio; Benoit L. Salomon; Gilles Marodon

doi:10.1371/journal.pone.0153682

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Peer-reviewed

Research Article

Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression

Jérémie D. Goldstein,

Current address: Institute for Biomedecine, Bellinzona, Switzerland

Affiliation Sorbonne Universités, UPMC Univ Paris 06, UMR-S CR7, Centre d’Immunologie et des Maladies Infectieuses (CIMI), INSERM U1135, CNRS ERL 8255, Paris, France
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Aude Burlion,

Affiliation Sorbonne Universités, UPMC Univ Paris 06, UMR-S CR7, Centre d’Immunologie et des Maladies Infectieuses (CIMI), INSERM U1135, CNRS ERL 8255, Paris, France
⨯
Bruno Zaragoza,

Affiliation Sorbonne Universités, UPMC Univ Paris 06, UMR-S CR7, Centre d’Immunologie et des Maladies Infectieuses (CIMI), INSERM U1135, CNRS ERL 8255, Paris, France
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Kélhia Sendeyo,

Affiliation Sorbonne Universités, UPMC Univ Paris 06, UMR-S CR7, Centre d’Immunologie et des Maladies Infectieuses (CIMI), INSERM U1135, CNRS ERL 8255, Paris, France
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Julia K. Polansky,

Current address: Experimental Rheumatology, German Rheumatism Research Center, Charitéplatz 1, Berlin, Germany

Affiliation Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany
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Jochen Huehn,

Affiliation Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany
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Eliane Piaggio,

Affiliation INSERM U932, Institut Curie, Paris, France
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Benoit L. Salomon,

Affiliation Sorbonne Universités, UPMC Univ Paris 06, UMR-S CR7, Centre d’Immunologie et des Maladies Infectieuses (CIMI), INSERM U1135, CNRS ERL 8255, Paris, France
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Gilles Marodon

* E-mail: gilles.marodon@upmc.fr

Affiliation Sorbonne Universités, UPMC Univ Paris 06, UMR-S CR7, Centre d’Immunologie et des Maladies Infectieuses (CIMI), INSERM U1135, CNRS ERL 8255, Paris, France

http://orcid.org/0000-0003-4889-6785

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Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression

Jérémie D. Goldstein,
Aude Burlion,
Bruno Zaragoza,
Kélhia Sendeyo,
Julia K. Polansky,
Jochen Huehn,
Eliane Piaggio,
Benoit L. Salomon,
Gilles Marodon

Published: April 14, 2016
https://doi.org/10.1371/journal.pone.0153682

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25 Apr 2016
11:05 GMT
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Error in figure 1 panel B Posted by marodon on 25 Apr 2016 at 11:05 GMT

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Regulatory T cells
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Messenger RNA
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Signal inhibition
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Cloning
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T cells
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Cell staining
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