Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

Bao Cao; Lars Christophersen; Mette Kolpen; Peter Østrup Jensen; Kim Sneppen; Niels Høiby; Claus Moser; Thomas Sams

doi:10.1371/journal.pone.0153616

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Open Access

Peer-reviewed

Research Article

Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

Bao Cao,

Affiliation Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark
⨯
Lars Christophersen,

Affiliation Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark
⨯
Mette Kolpen,

Affiliations Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark, Department of Immunology and Microbiology, UC-CARE, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark

http://orcid.org/0000-0001-5575-0384

⨯
Peter Østrup Jensen,

Affiliation Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark
⨯
Kim Sneppen,

Affiliation Niels Bohr Institute, University of Copenhagen, Blegdamsvej 17, DK-2100 Copenhagen, Denmark
⨯
Niels Høiby,

Affiliations Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark, Department of Immunology and Microbiology, UC-CARE, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark
⨯
Claus Moser,

Affiliation Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, DK-2100 Copenhagen, Denmark
⨯
Thomas Sams

* E-mail: tsams@dtu.dk

Affiliation Biomedical Engineering, Dept. of Electrical Engineering, Technical University of Denmark, DK-2800 Lyngby, Denmark

http://orcid.org/0000-0002-6316-2539

⨯

Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

Bao Cao,
Lars Christophersen,
Mette Kolpen,
Peter Østrup Jensen,
Kim Sneppen,
Niels Høiby,
Claus Moser,
Thomas Sams

Published: April 21, 2016
https://doi.org/10.1371/journal.pone.0153616

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