How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains

Roy Combe; John Mudgett; Lahcen El Fertak; Marie-france Champy; Estelle Ayme-Dietrich; Benoit Petit-Demoulière; Tania Sorg; Yann Herault; Jeffrey B. Madwed; Laurent Monassier

doi:10.1371/journal.pone.0153472

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Open Access

Peer-reviewed

Research Article

How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains

Roy Combe ,

* E-mail: roy.combe@epfl.ch

Current address: Center of Phenogenomics, Ecole Polytechnique Fédérale de Lausanne, Switzerland.

Affiliation Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France
⨯
John Mudgett,

Affiliation Merck Research Laboratories, Kenilworth, New Jersey, United States of America
⨯
Lahcen El Fertak,

Affiliation Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France
⨯
Marie-france Champy,

Affiliation Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France
⨯
Estelle Ayme-Dietrich,

Affiliation Laboratoire de Neurobiologie et Pharmacologie Cardiovasculaire, Faculté de Médecine, Fédération de Médecine Translationnelle, Université et Centre Hospitalier Universitaire de Strasbourg, France
⨯
Benoit Petit-Demoulière,

Affiliation Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France
⨯
Tania Sorg,

Affiliation Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France
⨯
Yann Herault,

Affiliation Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France
⨯
Jeffrey B. Madwed,

Affiliation Merck Research Laboratories, Kenilworth, New Jersey, United States of America
⨯
Laurent Monassier

Affiliations Institut Clinique de la Souris, Institut de Génétique et de Biologie Moléculaire, Université de Strasbourg, Illkirch, France, Laboratoire de Neurobiologie et Pharmacologie Cardiovasculaire, Faculté de Médecine, Fédération de Médecine Translationnelle, Université et Centre Hospitalier Universitaire de Strasbourg, France
⨯

How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains

Roy Combe,
John Mudgett,
Lahcen El Fertak,
Marie-france Champy,
Estelle Ayme-Dietrich,
Benoit Petit-Demoulière,
Tania Sorg,
Yann Herault,
Jeffrey B. Madwed,
Laurent Monassier

Published: April 18, 2016
https://doi.org/10.1371/journal.pone.0153472

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Diet
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Sodium chloride
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Blood pressure
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Blood plasma
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Aldosterone
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Circadian rhythms
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Heart rate
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