Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire

Nyambayar Dashtsoodol; Tomokuni Shigeura; Ritsuko Ozawa; Michishige Harada; Satoshi Kojo; Takashi Watanabe; Haruhiko Koseki; Manabu Nakayama; Osamu Ohara; Masaru Taniguchi

doi:10.1371/journal.pone.0153347

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Open Access

Peer-reviewed

Research Article

Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire

Nyambayar Dashtsoodol,

Affiliations Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan, Core Research Laboratory, Mongolian National University of Medical Sciences (MNUMS), Ulaanbaatar, 14210, Mongolia
⨯
Tomokuni Shigeura,

Affiliation Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Ritsuko Ozawa,

Affiliation Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Michishige Harada,

Affiliation Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Satoshi Kojo,

Affiliation Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Takashi Watanabe,

Affiliation Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Haruhiko Koseki,

Affiliation Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Manabu Nakayama,

Affiliation Department of Human Genome Research, Kazusa DNA Research Institute, Kisarazu, Chiba, 292–0818, Japan
⨯
Osamu Ohara,

Affiliation Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯
Masaru Taniguchi

* E-mail: masaru.taniguchi@riken.jp

Affiliation Laboratory for Immune Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, 230–0045, Japan
⨯

Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire

Nyambayar Dashtsoodol,
Tomokuni Shigeura,
Ritsuko Ozawa,
Michishige Harada,
Satoshi Kojo,
Takashi Watanabe,
Haruhiko Koseki,
Manabu Nakayama,
Osamu Ohara,
Masaru Taniguchi

Published: April 11, 2016
https://doi.org/10.1371/journal.pone.0153347

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