Activation of Brainstem Pro-opiomelanocortin Neurons Produces Opioidergic Analgesia, Bradycardia and Bradypnoea

Open Access

Peer-reviewed

Research Article

Serena Cerritelli,

Affiliation School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences Building, University of Bristol, Bristol, BS8 1TD, United Kingdom
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Stefan Hirschberg,

Affiliation School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences Building, University of Bristol, Bristol, BS8 1TD, United Kingdom
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Rob Hill,

Affiliation School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences Building, University of Bristol, Bristol, BS8 1TD, United Kingdom
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Nina Balthasar,

Affiliation School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences Building, University of Bristol, Bristol, BS8 1TD, United Kingdom
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Anthony E. Pickering

* E-mail: Tony.Pickering@bristol.ac.uk

Affiliations School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences Building, University of Bristol, Bristol, BS8 1TD, United Kingdom, Department of Anaesthesia, University Hospitals Bristol, Bristol, BS2 8HW, United Kingdom
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Neurons
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Opioids
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Bradycardia
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Brainstem
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Cerebellar nuclei
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Analgesia
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Nerve fibers
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Heart rate
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