High Levels of Sample-to-Sample Variation Confound Data Analysis for Non-Invasive Prenatal Screening of Fetal Microdeletions

Open Access

Peer-reviewed

Research Article

Tianjiao Chu,

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, United States of America, Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯
Suveyda Yeniterzi,

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, United States of America, Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯
Svetlana A. Yatsenko,

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, United States of America, Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯
Mary Dunkel,

Affiliation Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯
Patricia A. Shaw,

Affiliation Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯
Kimberly D. Bunce,

Affiliation Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯
David G. Peters

* E-mail: dgp6@pitt.edu

Affiliations Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, United States of America, Center for Fetal Medicine, Magee-Womens Research Institute, Pittsburgh, PA, United States of America
⨯

Reader Comments (0)

Human genomics
Is the Subject Area "Human genomics" applicable to this article?

Thanks for your feedback.
Genomic libraries
Is the Subject Area "Genomic libraries" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Chorionic villus sampling
Is the Subject Area "Chorionic villus sampling" applicable to this article?

Thanks for your feedback.
Copy number variation
Is the Subject Area "Copy number variation" applicable to this article?

Thanks for your feedback.
Genome sequencing
Is the Subject Area "Genome sequencing" applicable to this article?

Thanks for your feedback.