Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice

Shweta Jain; Giljun Park; Thomas J. Sproule; Gregory J. Christianson; Caroline M. Leeth; Hongsheng Wang; Derry C. Roopenian; Herbert C. Morse III

doi:10.1371/journal.pone.0153059

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Open Access

Peer-reviewed

Research Article

Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice

Shweta Jain,

Affiliation Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States of America
⨯
Giljun Park,

Affiliations The Jackson Laboratory, Bar Harbor, ME, United States of America, Hematology Research Unit, University of Helsinki, Helsinki University Central Hospital Cancer Center, Biomedicum Helsinki 1, Haartmaninkatu, Helsinki, Finland
⨯
Thomas J. Sproule,

Affiliation The Jackson Laboratory, Bar Harbor, ME, United States of America
⨯
Gregory J. Christianson,

Affiliation The Jackson Laboratory, Bar Harbor, ME, United States of America
⨯
Caroline M. Leeth,

Affiliation Department of Animal and Poultry Sciences, College of Agriculture and Life Sciences, Virginia Tech, Blacksburg, VA, United States of America
⨯
Hongsheng Wang,

Affiliation Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States of America
⨯
Derry C. Roopenian ,

* E-mail: hmorse@niaid.nih.gov (HCM); dcr@jax.org (DCR)

Affiliation The Jackson Laboratory, Bar Harbor, ME, United States of America
⨯
Herbert C. Morse III

* E-mail: hmorse@niaid.nih.gov (HCM); dcr@jax.org (DCR)

Affiliation Virology and Cellular Immunology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States of America
⨯

Interleukin 6 Accelerates Mortality by Promoting the Progression of the Systemic Lupus Erythematosus-Like Disease of BXSB.Yaa Mice

Shweta Jain,
Giljun Park,
Thomas J. Sproule,
Gregory J. Christianson,
Caroline M. Leeth,
Hongsheng Wang,
Derry C. Roopenian,
Herbert C. Morse III

Published: April 6, 2016
https://doi.org/10.1371/journal.pone.0153059

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