Molecular Dynamics Simulations to Investigate the Influences of Amino Acid Mutations on Protein Three-Dimensional Structures of Cytochrome P450 2D6.1, 2, 10, 14A, 51, and 62

• Shuichi Fukuyoshi ,

  Contributed equally to this work with: Shuichi Fukuyoshi, Masaharu Kometani

  Affiliation Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, 920–1192, Japan

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• Masaharu Kometani ,

  Contributed equally to this work with: Shuichi Fukuyoshi, Masaharu Kometani

  Affiliation Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, 920–1192, Japan

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• Yurie Watanabe,

  Affiliation Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, 920–1192, Japan

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• Masahiro Hiratsuka,

  Affiliation Graduate School of Pharmaceutical Sciences, Tohoku University, 6–3 Aoba, Aramaki, Aoba-ku, Sendai, 980–8578, Japan

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• Noriyuki Yamaotsu,

  Affiliation School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108–8641, Japan

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• Shuichi Hirono,

  Affiliation School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108–8641, Japan

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• Noriyoshi Manabe,

  Affiliation Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981–8558, Japan

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• Ohgi Takahashi,

  Affiliation Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi, 981–8558, Japan

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• Akifumi Oda

  * E-mail: oda@p.kanazawa-u.ac.jp

  Affiliations Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa, 920–1192, Japan, Institute for Protein Research, Osaka University, 3–2 Yamadaoka, Suita, Osaka, 565–0871, Japan

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