Beneficial Effects of Anti-Interleukin-6 Antibodies on Impaired Gastrointestinal Motility, Inflammation and Increased Colonic Permeability in a Murine Model of Sepsis Are Most Pronounced When Administered in a Preventive Setup

• Sara Nullens,

  Affiliation Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium

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• Michael Staessens,

  Affiliation Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium

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• Cédric Peleman,

  Affiliation Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium

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• Philip Plaeke,

  Affiliation Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium

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• Surbhi Malhotra-Kumar,

  Affiliation Laboratory of Medical Microbiology, University of Antwerp, Antwerp, Belgium

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• Sven Francque,

  Affiliations Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium, Antwerp University Hospital, Department of Gastroenterology and Hepatology, Antwerp, Belgium

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• Joris G. De Man,

  Affiliation Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium

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• Benedicte Y. De Winter

  * E-mail: benedicte.dewinter@uantwerpen.be

  Affiliation Laboratory of Experimental Medicine and Pediatrics, Division of Gastroenterology, University of Antwerp, Antwerp, Belgium

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