Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation

Chih-Hsin Lai; Ying-Jung J. Lai; Feng-Pai Chou; Hsiang-Hua D. Chang; Chun-Che Tseng; Michael D. Johnson; Jehng-Kang Wang; Chen-Yong Lin

doi:10.1371/journal.pone.0152904

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Open Access

Peer-reviewed

Research Article

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation

Chih-Hsin Lai,

Affiliations Department of Dentistry Renai Branch, Taipei City Hospital, Taipei, Taiwan, Graduate Institute of Medical Sciences National Defense Medical Center, Taipei, Taiwan
⨯
Ying-Jung J. Lai,

Affiliation Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, United States of America
⨯
Feng-Pai Chou,

Affiliation Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, United States of America
⨯
Hsiang-Hua D. Chang,

Affiliations Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, United States of America, Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan
⨯
Chun-Che Tseng,

Affiliation Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, United States of America
⨯
Michael D. Johnson,

Affiliation Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, United States of America
⨯
Jehng-Kang Wang ,

* E-mail: lincy@georgetown.edu (CYL); jkwang@ndmctsgh.edu.tw (JKW)

Affiliations Graduate Institute of Medical Sciences National Defense Medical Center, Taipei, Taiwan, Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan
⨯
Chen-Yong Lin

* E-mail: lincy@georgetown.edu (CYL); jkwang@ndmctsgh.edu.tw (JKW)

Affiliation Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, United States of America
⨯

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation

Chih-Hsin Lai,
Ying-Jung J. Lai,
Feng-Pai Chou,
Hsiang-Hua D. Chang,
Chun-Che Tseng,
Michael D. Johnson,
Jehng-Kang Wang,
Chen-Yong Lin

Published: April 4, 2016
https://doi.org/10.1371/journal.pone.0152904

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Proteases
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Epithelial cells
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Serine proteases
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Gel electrophoresis
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