Cycloart-24-ene-26-ol-3-one, a New Cycloartane Isolated from Leaves of Aglaia exima Triggers Tumour Necrosis Factor-Receptor 1-Mediated Caspase-Dependent Apoptosis in Colon Cancer Cell Line

• Kok Hoong Leong ,

  Contributed equally to this work with: Kok Hoong Leong, Chung Yeng Looi

  Affiliations Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, Center for Natural Product and Drug Discovery (CENAR), Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia

  http://orcid.org/0000-0002-7317-6117

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• Chung Yeng Looi ,

  Contributed equally to this work with: Kok Hoong Leong, Chung Yeng Looi

  Affiliation Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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• Xe-Min Loong,

  Affiliation Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia

  ⨯
• Foo Kit Cheah,

  Affiliation Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

  ⨯
• Unang Supratman,

  Affiliation Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor, Indonesia

  ⨯
• Marc Litaudon ,

  ¶‡ These authors are senior authors on this work.

  Affiliation Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS 1, Avenue de la Terrasse, Gif-sur-Yvette Cedex, France

  ⨯
• Mohd Rais Mustafa ,

  ¶‡ These authors are senior authors on this work.

  Affiliations Center for Natural Product and Drug Discovery (CENAR), Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

  ⨯
• Khalijah Awang

  * E-mail: khalijah@um.edu.my

  ¶‡ These authors are senior authors on this work.

  Affiliations Center for Natural Product and Drug Discovery (CENAR), Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia, Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia

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