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Open Access

Peer-reviewed

Research Article

Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire

Xiao Liu ,

Contributed equally to this work with: Xiao Liu, Wei Zhang, Xiaojing Zeng

Affiliations BGI-Shenzhen, Shenzhen, 518083, China, Department of Biology, University of Copenhagen, Copenhagen, Denmark
⨯
Wei Zhang ,

Contributed equally to this work with: Xiao Liu, Wei Zhang, Xiaojing Zeng

Affiliations BGI-Shenzhen, Shenzhen, 518083, China, Shenzhen Key Laboratory of Transomics Biotechnologies, BGI-Shenzhen, Shenzhen, 518083, China
⨯
Xiaojing Zeng ,

Contributed equally to this work with: Xiao Liu, Wei Zhang, Xiaojing Zeng

Affiliations BGI-Shenzhen, Shenzhen, 518083, China, Shenzhen Key Laboratory of Transomics Biotechnologies, BGI-Shenzhen, Shenzhen, 518083, China
⨯
Ruifang Zhang,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Yuanping Du,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Xueyu Hong,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Hongzhi Cao,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Zheng Su,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Changxi Wang,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Jinghua Wu,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Chao Nie,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Xun Xu,

Affiliation BGI-Shenzhen, Shenzhen, 518083, China
⨯
Karsten Kristiansen

* E-mail: kk@bio.ku.dk

Affiliation Department of Biology, University of Copenhagen, Copenhagen, Denmark
⨯

Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire

Xiao Liu,
Wei Zhang,
Xiaojing Zeng,
Ruifang Zhang,
Yuanping Du,
Xueyu Hong,
Hongzhi Cao,
Zheng Su,
Changxi Wang,
Jinghua Wu

x

Published: March 28, 2016
https://doi.org/10.1371/journal.pone.0152464

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Cloning
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Polymerase chain reaction
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Nucleotide sequencing
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T cells
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T cell receptors
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Protein sequencing
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Sequence alignment
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Signal amplification
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