Estrogen Receptor Expression Is Associated with DNA Repair Capacity in Breast Cancer

Jaime Matta; Luisa Morales; Carmen Ortiz; Damian Adams; Wanda Vargas; Patricia Casbas; Julie Dutil; Miguel Echenique; Erick Suárez

doi:10.1371/journal.pone.0152422

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Open Access

Peer-reviewed

Research Article

Estrogen Receptor Expression Is Associated with DNA Repair Capacity in Breast Cancer

Jaime Matta ,

* E-mail: jmatta@psm.edu

Affiliations Department of Basic Sciences, Division of Pharmacology & Toxicology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America, Department of Basic Sciences, Division of Cancer Biology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America
⨯
Luisa Morales,

Affiliation Public Health Program, Ponce Health Sciences University, Ponce, Puerto Rico, United States of America
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Carmen Ortiz,

Affiliations Department of Basic Sciences, Division of Pharmacology & Toxicology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America, Department of Basic Sciences, Division of Cancer Biology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America
⨯
Damian Adams,

Affiliations Department of Basic Sciences, Division of Pharmacology & Toxicology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America, Department of Basic Sciences, Division of Cancer Biology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America
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Wanda Vargas,

Affiliations Department of Basic Sciences, Division of Pharmacology & Toxicology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America, Department of Basic Sciences, Division of Cancer Biology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America
⨯
Patricia Casbas,

Affiliations Department of Basic Sciences, Division of Cancer Biology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America, Department of Basic Sciences, Division of Biochemistry, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America
⨯
Julie Dutil,

Affiliations Department of Basic Sciences, Division of Cancer Biology, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America, Department of Basic Sciences, Division of Biochemistry, Ponce Health Sciences University-School of Medicine, Ponce Research Institute, Ponce, Puerto Rico, United States of America
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Miguel Echenique,

Affiliation Auxilio Mutuo Hospital, San Juan, Puerto Rico, United States of America
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Erick Suárez

Affiliation Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico, United States of America
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Estrogen Receptor Expression Is Associated with DNA Repair Capacity in Breast Cancer

Jaime Matta,
Luisa Morales,
Carmen Ortiz,
Damian Adams,
Wanda Vargas,
Patricia Casbas,
Julie Dutil,
Miguel Echenique,
Erick Suárez

Published: March 31, 2016
https://doi.org/10.1371/journal.pone.0152422

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Breast cancer
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DNA repair
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Cancer treatment
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Lymphocytes
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DNA damage
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Estrogens
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Cancers and neoplasms
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Hormones
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