Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons

Wei Jiang; Tao Luo; Sheng Li; Yue Zhou; Xiu-Yin Shen; Feng He; Jie Xu; Hua-Qiao Wang

doi:10.1371/journal.pone.0152371

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Open Access

Peer-reviewed

Research Article

Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons

Wei Jiang ,

Contributed equally to this work with: Wei Jiang, Tao Luo

Affiliations Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China, Department of Anatomy and Histoembryology, Zhaoqing Medical College, Zhaoqing, Guangdong, 526020, China
⨯
Tao Luo ,

Contributed equally to this work with: Wei Jiang, Tao Luo

Affiliation Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯
Sheng Li,

Affiliation Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯
Yue Zhou,

Affiliation Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯
Xiu-Yin Shen,

Affiliation Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯
Feng He ,

* E-mail: hefeng@mail.sysu.edu.cn (FH); wanghq@mail.sysu.edu.cn (HQW)

Affiliation School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong, 510006, China
⨯
Jie Xu,

Affiliation Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯
Hua-Qiao Wang

* E-mail: hefeng@mail.sysu.edu.cn (FH); wanghq@mail.sysu.edu.cn (HQW)

Affiliation Department of Anatomy and Neurobiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯

Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons

Wei Jiang,
Tao Luo,
Sheng Li,
Yue Zhou,
Xiu-Yin Shen,
Feng He,
Jie Xu,
Hua-Qiao Wang

Published: April 6, 2016
https://doi.org/10.1371/journal.pone.0152371

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