A Personalized Approach to Biological Therapy Using Prediction of Clinical Response Based on MRP8/14 Serum Complex Levels in Rheumatoid Arthritis Patients

S. C. Nair; P. M. J. Welsing; I. Y. K. Choi; J. Roth; D. Holzinger; J. W. J. Bijlsma; J. M. van Laar; D. M. Gerlag; F. P. J. G. Lafeber; P. P. Tak

doi:10.1371/journal.pone.0152362

Loading metrics

Open Access

Peer-reviewed

Research Article

A Personalized Approach to Biological Therapy Using Prediction of Clinical Response Based on MRP8/14 Serum Complex Levels in Rheumatoid Arthritis Patients

S. C. Nair ,

* E-mail: sandyn26@gmail.com

Affiliation Department of Rheumatology and Clinical Immunology, University Medical Center, Utrecht, The Netherlands
⨯
P. M. J. Welsing,

Affiliation Department of Rheumatology and Clinical Immunology, University Medical Center, Utrecht, The Netherlands
⨯
I. Y. K. Choi,

Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, the Netherlands
⨯
J. Roth,

Affiliation Institute of Immunology, University Hospital Muenster, Muenster, Germany
⨯
D. Holzinger,

Affiliation Department of Pediatric Rheumatology and Immunology, University Children's Hospital Muenster, Muenster, Germany
⨯
J. W. J. Bijlsma,

Affiliation Department of Rheumatology and Clinical Immunology, University Medical Center, Utrecht, The Netherlands
⨯
J. M. van Laar,

Affiliation Department of Rheumatology and Clinical Immunology, University Medical Center, Utrecht, The Netherlands
⨯
D. M. Gerlag,

Current address: Clinical Unit Cambridge, GSK, Cambridge, United Kingdom

Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, the Netherlands
⨯
F. P. J. G. Lafeber,

Affiliation Department of Rheumatology and Clinical Immunology, University Medical Center, Utrecht, The Netherlands
⨯
P. P. Tak

Current address: GSK Research & Development, Stevenage, United Kingdom; University of Cambridge, Cambridge, United Kingdom; Ghent University, Ghent, Belgium

Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, the Netherlands
⨯

A Personalized Approach to Biological Therapy Using Prediction of Clinical Response Based on MRP8/14 Serum Complex Levels in Rheumatoid Arthritis Patients

S. C. Nair,
P. M. J. Welsing,
I. Y. K. Choi,
J. Roth,
D. Holzinger,
J. W. J. Bijlsma,
J. M. van Laar,
D. M. Gerlag,
F. P. J. G. Lafeber,
P. P. Tak

Published: March 30, 2016
https://doi.org/10.1371/journal.pone.0152362

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.
Forecasting
Is the Subject Area "Forecasting" applicable to this article?

Thanks for your feedback.
Rheumatoid arthritis
Is the Subject Area "Rheumatoid arthritis" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
C-reactive proteins
Is the Subject Area "C-reactive proteins" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Algorithms
Is the Subject Area "Algorithms" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.