TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)

Xi-Lin Chen; Daniel Serrano; Farnaz Ghobadi; Marian Mayhue; Kasper Hoebe; Subburaj Ilangumaran; Sheela Ramanathan

doi:10.1371/journal.pone.0151837

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Open Access

Peer-reviewed

Research Article

TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)

Xi-Lin Chen,

Current address: Institute for Research in Immunology and Cancer, Department of Pathology and Cell Biology, Université de Montréal, Montreal, H3T 1J4, QC, Canada

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Daniel Serrano,

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Farnaz Ghobadi,

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
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Marian Mayhue,

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Kasper Hoebe,

Affiliation Department of Pediatrics, Division of Cellular and Molecular Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States of America
⨯
Subburaj Ilangumaran,

Affiliations Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada, Centre de recherche clinique, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Sheela Ramanathan

* E-mail: Sheela.Ramanathan@Usherbrooke.ca

Affiliations Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada, Centre de recherche clinique, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯

TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)

Xi-Lin Chen,
Daniel Serrano,
Farnaz Ghobadi,
Marian Mayhue,
Kasper Hoebe,
Subburaj Ilangumaran,
Sheela Ramanathan

Published: March 29, 2016
https://doi.org/10.1371/journal.pone.0151837

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