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Open Access
Peer-reviewed
Research Article
CD117+ Dendritic and Mast Cells Are Dependent on RasGRP4 to Function as Accessory Cells for Optimal Natural Killer Cell-Mediated Responses to Lipopolysaccharide
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Saijun Zhou ,
¶‡ SZ and KT are joint first authors on this work. RLS and SAK are joint senior authors on this work.
Affiliations Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia, Laboratory of Hormones and Development (Ministry of Health), Metabolic Hospital and Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, TJ, China
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Kumiko Tanaka ,
¶‡ SZ and KT are joint first authors on this work. RLS and SAK are joint senior authors on this work.
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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Meredith O’Keeffe,
Affiliation Dendritic Cell Research Laboratory, Immunity Vaccines and Immunisation, Burnet Institute, Prahran, Melbourne, Victoria, Australia
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Miao Qi,
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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Fatima El-Assaad,
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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James C. Weaver,
Affiliations Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia, Department of Cardiology, St. George Hospital, Sydney, New South Wales, Australia
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Gang Chen,
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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Christopher Weatherall,
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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Ying Wang,
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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Bill Giannakopoulos,
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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Liming Chen,
Affiliation Laboratory of Hormones and Development (Ministry of Health), Metabolic Hospital and Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, TJ, China
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DeMint Yu,
Affiliation Laboratory of Hormones and Development (Ministry of Health), Metabolic Hospital and Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, TJ, China
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Matthew J. Hamilton,
Affiliations School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia, Division of Gastroenterology, Brigham and Women’s Hospital, Boston, MA, United States of America
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Lislaine A. Wensing,
Affiliation Departament of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, Brazil
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Richard L. Stevens ,
¶‡ SZ and KT are joint first authors on this work. RLS and SAK are joint senior authors on this work.
Affiliations Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
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Steven A. Krilis
* E-mail: s.krilis@unsw.edu.au
¶‡ SZ and KT are joint first authors on this work. RLS and SAK are joint senior authors on this work.
Affiliation Department of Infectious Diseases, Immunology, and Sexual Health, St. George Hospital, and the St. George and Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
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CD117+ Dendritic and Mast Cells Are Dependent on RasGRP4 to Function as Accessory Cells for Optimal Natural Killer Cell-Mediated Responses to Lipopolysaccharide
- Saijun Zhou,
- Kumiko Tanaka,
- Meredith O’Keeffe,
- Miao Qi,
- Fatima El-Assaad,
- James C. Weaver,
- Gang Chen,
- Christopher Weatherall,
- Ying Wang,
- Bill Giannakopoulos
- Published: March 16, 2016
- https://doi.org/10.1371/journal.pone.0151638