Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes

Katherine J. Zappia; Sheldon R. Garrison; Oleg Palygin; Andy D. Weyer; Marie E. Barabas; Michael W. Lawlor; Alexander Staruschenko; Cheryl L. Stucky

doi:10.1371/journal.pone.0151602

Loading metrics

Open Access

Peer-reviewed

Research Article

Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes

Katherine J. Zappia ,

Contributed equally to this work with: Katherine J. Zappia, Sheldon R. Garrison

* E-mail: kzappia@mcw.edu (KJZ); cstucky@mcw.edu (CLS)

Affiliation Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Sheldon R. Garrison ,

Contributed equally to this work with: Katherine J. Zappia, Sheldon R. Garrison

Affiliation Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Oleg Palygin,

Affiliation Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Andy D. Weyer,

Affiliation Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Marie E. Barabas,

Affiliation Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Michael W. Lawlor,

Affiliation Division of Pediatric Pathology, Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Alexander Staruschenko,

Affiliation Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯
Cheryl L. Stucky

* E-mail: kzappia@mcw.edu (KJZ); cstucky@mcw.edu (CLS)

Affiliation Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
⨯

Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes

Katherine J. Zappia,
Sheldon R. Garrison,
Oleg Palygin,
Andy D. Weyer,
Marie E. Barabas,
Michael W. Lawlor,
Alexander Staruschenko,
Cheryl L. Stucky

Published: March 15, 2016
https://doi.org/10.1371/journal.pone.0151602

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Epidermis
Is the Subject Area "Epidermis" applicable to this article?

Thanks for your feedback.
Keratinocytes
Is the Subject Area "Keratinocytes" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Mice
Is the Subject Area "Mice" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Sensory neurons
Is the Subject Area "Sensory neurons" applicable to this article?

Thanks for your feedback.
Neurons
Is the Subject Area "Neurons" applicable to this article?

Thanks for your feedback.
Sensory perception
Is the Subject Area "Sensory perception" applicable to this article?

Thanks for your feedback.