A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells

• Andrea Buchfellner ,

  Contributed equally to this work with: Andrea Buchfellner, Larisa Yurlova

  Affiliation ChromoTek GmbH, IZB, Planegg, Martinsried, Germany

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• Larisa Yurlova ,

  Contributed equally to this work with: Andrea Buchfellner, Larisa Yurlova

  Affiliation ChromoTek GmbH, IZB, Planegg, Martinsried, Germany

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• Stefan Nüske,

  Affiliation Livestock Center of the Faculty of Veterinary Medicine, Ludwig Maximilians University, Munich, Germany

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• Armin M. Scholz,

  Affiliation Livestock Center of the Faculty of Veterinary Medicine, Ludwig Maximilians University, Munich, Germany

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• Jacqueline Bogner,

  Affiliation ChromoTek GmbH, IZB, Planegg, Martinsried, Germany

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• Benjamin Ruf,

  Affiliation ChromoTek GmbH, IZB, Planegg, Martinsried, Germany

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• Kourosh Zolghadr,

  Affiliation ChromoTek GmbH, IZB, Planegg, Martinsried, Germany

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• Sophie E. Drexler,

  Affiliation Department of Radiation Oncology, Ludwig Maximilians University, Munich, Germany

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• Guido A. Drexler,

  Affiliation Department of Radiation Oncology, Ludwig Maximilians University, Munich, Germany

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• Stefanie Girst,

  Affiliation Institute for Applied Physics and Metrology, Bundeswehr University Munich, Neubiberg, Germany

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• Christoph Greubel,

  Affiliation Institute for Applied Physics and Metrology, Bundeswehr University Munich, Neubiberg, Germany

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• Judith Reindl,

  Affiliation Institute for Applied Physics and Metrology, Bundeswehr University Munich, Neubiberg, Germany

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• Christian Siebenwirth,

  Affiliation Department of Radiation Oncology, Klinikum rechts der Isar, Technical University Munich, Munich, Germany

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• Tina Romer ,

  * E-mail: t.romer@chromotek.com

  Affiliation ChromoTek GmbH, IZB, Planegg, Martinsried, Germany

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• Anna A. Friedl ,

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Radiation Oncology, Ludwig Maximilians University, Munich, Germany, Clinical Cooperation Group ‘Personalized Radiotherapy of Head and Neck Cancer’, Helmholtz Center Munich, Neuherberg, Germany

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•  [ ... ],
• Ulrich Rothbauer

  ¶‡ These authors also contributed equally to this work.

  Affiliations Natural and Medical Institute at the University of Tuebingen, Reutlingen, Germany, Pharmaceutical Biotechnology, University of Tuebingen, Tuebingen, Germany

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