Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization

Open Access

Peer-reviewed

Research Article

Kazumi Take ,

* E-mail: kazumi.take@takeda.com

Affiliation Cardiovascular and Metabolic Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Taisuke Mochida,

Affiliation Cardiovascular and Metabolic Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Toshiyuki Maki,

Affiliation Cardiovascular and Metabolic Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Yoshinori Satomi,

Affiliation Integrated Technology Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Megumi Hirayama,

Affiliation Integrated Technology Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Masanori Nakakariya,

Affiliation DMPK Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Nobuyuki Amano,

Affiliation DMPK Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Ryutaro Adachi,

Affiliation Biomolecular Research Laboratories, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Kenjiro Sato,

Affiliation Cardiovascular and Metabolic Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Tomoyuki Kitazaki,

Affiliation Cardiovascular and Metabolic Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯
Shiro Takekawa

Affiliation Cardiovascular and Metabolic Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Fujisawa, Japan
⨯

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Gastrointestinal tract
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Blood plasma
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Insulin
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Small intestine
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Food
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Body weight
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Fats
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Glucose
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