CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells

Zhiying Ai; Jingjing Shao; Yongyan Wu; Mengying Yu; Juan Du; Xiaoyan Shi; Xinglong Shi; Yong Zhang; Zekun Guo

doi:10.1371/journal.pone.0150936

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Open Access

Peer-reviewed

Research Article

CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells

Zhiying Ai,

Affiliations College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Jingjing Shao,

Affiliations College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Yongyan Wu,

Affiliations College of Veterinary Medicine, Northwest A& F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Mengying Yu,

Affiliations College of Veterinary Medicine, Northwest A& F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Juan Du,

Affiliations College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Xiaoyan Shi,

Affiliations College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Xinglong Shi,

Affiliations College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Yong Zhang,

Affiliations College of Veterinary Medicine, Northwest A& F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯
Zekun Guo

* E-mail: gzk@nwsuaf.edu.cn

Affiliations College of Veterinary Medicine, Northwest A& F University, Yangling, Shaanxi, China, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A& F University, Yangling, Shaanxi, China
⨯

CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells

Zhiying Ai,
Jingjing Shao,
Yongyan Wu,
Mengying Yu,
Juan Du,
Xiaoyan Shi,
Xinglong Shi,
Yong Zhang,
Zekun Guo

Published: March 3, 2016
https://doi.org/10.1371/journal.pone.0150936

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