The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization

Open Access

Peer-reviewed

Research Article

Vasileios A. Stamelos,

Affiliations Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom, University Hospital of North Midlands, Stoke-on-Trent, Staffordshire, United Kingdom
⨯
Natalie Fisher,

Affiliation Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom
⨯
Harnoor Bamrah,

Affiliation Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom
⨯
Carolyn Voisey,

Affiliations Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom, School of Pharmacy, Keele University, Keele, Staffordshire, United Kingdom
⨯
Joshua C. Price,

Affiliation Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom
⨯
William E. Farrell,

Affiliation Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom
⨯
Charles W. Redman,

Affiliation University Hospital of North Midlands, Stoke-on-Trent, Staffordshire, United Kingdom
⨯
Alan Richardson

* E-mail: a.richardson1@keele.ac.uk

Affiliations Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom, School of Pharmacy, Keele University, Keele, Staffordshire, United Kingdom
⨯

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Lysosomes
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Autophagic cell death
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Apoptosis
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Cell staining
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Cancer treatment
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Chloroquine
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Ovarian cancer
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Sex ratio
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