Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease

Lu Wang; Lan Guo; Lin Lu; Huili Sun; Muming Shao; Simon J. Beck; Lin Li; Janani Ramachandran; Yifeng Du; Heng Du

doi:10.1371/journal.pone.0150441

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Open Access

Peer-reviewed

Research Article

Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease

Lu Wang,

Affiliations Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080, Shandong University, Shandong Provincial Hospital, Jinan, Shandong Province, China, 250100
⨯
Lan Guo,

Affiliation Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080
⨯
Lin Lu,

Affiliations Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080, Shandong University, Shandong Provincial Hospital, Jinan, Shandong Province, China, 250100
⨯
Huili Sun,

Affiliations Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080, Shenzhen Traditional Medicine Hospital, Shenzhen, Guangdong Province, China, 518031
⨯
Muming Shao,

Affiliation Shenzhen Traditional Medicine Hospital, Shenzhen, Guangdong Province, China, 518031
⨯
Simon J. Beck,

Affiliation Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080
⨯
Lin Li,

Affiliation Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080
⨯
Janani Ramachandran,

Affiliation Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080
⨯
Yifeng Du,

Affiliation Shandong University, Shandong Provincial Hospital, Jinan, Shandong Province, China, 250100
⨯
Heng Du

* E-mail: heng.du@utdallas.edu

Affiliations Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX, United States of America, 75080, Shandong University, Shandong Provincial Hospital, Jinan, Shandong Province, China, 250100
⨯

Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease

Lu Wang,
Lan Guo,
Lin Lu,
Huili Sun,
Muming Shao,
Simon J. Beck,
Lin Li,
Janani Ramachandran,
Yifeng Du,
Heng Du

Published: March 4, 2016
https://doi.org/10.1371/journal.pone.0150441

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