Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression

Chiung-Kuei Huang; Yoshifumi Iwagami; Arihiro Aihara; Waihong Chung; Suzanne de la Monte; John-Michael Thomas; Mark Olsen; Rolf Carlson; Tunan Yu; Xiaoqun Dong; Jack Wands

doi:10.1371/journal.pone.0150336

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Peer-reviewed

Research Article

Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression

Chiung-Kuei Huang ,

Contributed equally to this work with: Chiung-Kuei Huang, Yoshifumi Iwagami, Arihiro Aihara

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
Yoshifumi Iwagami ,

Contributed equally to this work with: Chiung-Kuei Huang, Yoshifumi Iwagami, Arihiro Aihara

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
Arihiro Aihara ,

Contributed equally to this work with: Chiung-Kuei Huang, Yoshifumi Iwagami, Arihiro Aihara

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
Waihong Chung,

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
Suzanne de la Monte,

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
John-Michael Thomas,

Affiliation Department of Medical Chemistry, College of Pharmacy Glendale, Midwestern University, Glendale, Arizona, United States of America
⨯
Mark Olsen,

Affiliation Department of Medical Chemistry, College of Pharmacy Glendale, Midwestern University, Glendale, Arizona, United States of America
⨯
Rolf Carlson,

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
Tunan Yu,

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯
Xiaoqun Dong,

Current address: Department of Internal Medicine, College of Medicine, The University of Oklahoma Health Sciences Center, 975 NE10th Street, Oklahoma City, Oklahoma, United States of America

Affiliation Department of Biomedical and Pharmaceutical Science, College of Pharmacy, The University of Rhode Island, Pharmacy Building, 7 Greenhouse Road, Kingston, Rhode Island, United States of America
⨯
Jack Wands

* E-mail: Jack_Wands_MD@brown.edu

Affiliation Liver Research Center, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island, United States of America
⨯

Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression

Chiung-Kuei Huang,
Yoshifumi Iwagami,
Arihiro Aihara,
Waihong Chung,
Suzanne de la Monte,
John-Michael Thomas,
Mark Olsen,
Rolf Carlson,
Tunan Yu,
Xiaoqun Dong

Published: March 8, 2016
https://doi.org/10.1371/journal.pone.0150336

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