Evaluation of a Mixing versus a Cycling Strategy of Antibiotic Use in Critically-Ill Medical Patients: Impact on Acquisition of Resistant Microorganisms and Clinical Outcomes

• Nazaret Cobos-Trigueros ,

  * E-mail: fncobos@clinic.ub.es

  Affiliation Department of Infectious Diseases, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Mar Solé,

  Affiliation ISGlobal, Barcelona Center for International Health Research (CRESIB), Hospital Clínic - University of Barcelona, Barcelona, Spain

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• Pedro Castro,

  Affiliation Medical Intensive Care Unit, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Jorge Luis Torres,

  Current address: Department of Internal Medicine, University Hospital of Salamanca, Institute of Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.

  Affiliation Department of Infectious Diseases, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Mariano Rinaudo,

  Affiliation Medical Intensive Care Unit, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Elisa De Lazzari,

  Affiliation Health Biostatistic, Hospital Clínic-IDIBAPS, University of Barcelona, Barcelona, Spain

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• Laura Morata,

  Affiliation Department of Infectious Diseases, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Cristina Hernández,

  Affiliation Medical Intensive Care Unit, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Sara Fernández,

  Affiliation Medical Intensive Care Unit, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Alex Soriano,

  Affiliation Department of Infectious Diseases, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• José María Nicolás,

  Affiliation Medical Intensive Care Unit, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Josep Mensa,

  Affiliation Department of Infectious Diseases, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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• Jordi Vila,

  Affiliations ISGlobal, Barcelona Center for International Health Research (CRESIB), Hospital Clínic - University of Barcelona, Barcelona, Spain, Department of Clinical Microbiology, Hospital Clinic, School of Medicine, University of Barcelona, Barcelona, Spain

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• José Antonio Martínez

  Affiliation Department of Infectious Diseases, Hospital Clínic, IDIBAPS, Barcelona University, Barcelona, Spain

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