Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1

• Tamás Fodor,

  Affiliation Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary

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• Magdolna Szántó,

  Affiliations Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary, MTA-DE Cell Biology and Signaling Research Group, Debrecen, H-4032, Hungary

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• Omar Abdul-Rahman,

  Affiliations Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary, MTA-DE Cell Biology and Signaling Research Group, Debrecen, H-4032, Hungary

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• Lilla Nagy,

  Affiliations Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary, MTA-DE Cell Biology and Signaling Research Group, Debrecen, H-4032, Hungary

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• Ádám Dér,

  Affiliation Department of Oncology, Section of Radiation Therapy, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary

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• Borbála Kiss,

  Affiliation Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary

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• Peter Bai

  * E-mail: baip@med.unideb.hu

  Affiliations Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, H-4032, Hungary, MTA-DE Lendület Laboratory of Cellular Metabolism, Debrecen, H-4032, Hungary, Research Center for Molecular Medicine, University of Debrecen, Debrecen, H-4032, Hungary

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