Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion

Rebecca Sorber; Yaroslav Teper; Abisola Abisoye-Ogunniyan; Joshua J. Waterfall; Sean Davis; J. Keith Killian; Marbin Pineda; Satyajit Ray; Matt R. McCord; Holger Pflicke; Sandra Sczerba Burkett; Paul S. Meltzer; Udo Rudloff

doi:10.1371/journal.pone.0149833

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Peer-reviewed

Research Article

Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion

Rebecca Sorber ,

Contributed equally to this work with: Rebecca Sorber, Yaroslav Teper

Affiliation Thoracic & GI Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Yaroslav Teper ,

Contributed equally to this work with: Rebecca Sorber, Yaroslav Teper

Affiliation Thoracic & GI Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Abisola Abisoye-Ogunniyan,

Affiliations Thoracic & GI Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America, Department of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, Alabama 36088, United States of America
⨯
Joshua J. Waterfall,

Affiliation Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Sean Davis,

Affiliation Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
J. Keith Killian,

Affiliation Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Marbin Pineda,

Affiliation Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Satyajit Ray,

Affiliation Surgery Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Matt R. McCord,

Affiliation Thoracic & GI Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
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Holger Pflicke,

Affiliation Thoracic & GI Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
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Sandra Sczerba Burkett,

Affiliation Molecular Cytogenetic Section, MCGP, Center for Cancer Research, National Cancer Institute, NIH, Frederick, Maryland 21702, United States of America
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Paul S. Meltzer,

Affiliation Genetics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯
Udo Rudloff

* E-mail: rudloffu@mail.nih.gov

Affiliation Thoracic & GI Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, United States of America
⨯

Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion

Rebecca Sorber,
Yaroslav Teper,
Abisola Abisoye-Ogunniyan,
Joshua J. Waterfall,
Sean Davis,
J. Keith Killian,
Marbin Pineda,
Satyajit Ray,
Matt R. McCord,
Holger Pflicke

Published: March 10, 2016
https://doi.org/10.1371/journal.pone.0149833

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