Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

Open Access

Peer-reviewed

Research Article

Miranta Antoniou ,

* E-mail: Miranta.Antoniou@liverpool.ac.uk

Affiliations MRC North West Hub For Trials Methodology Research, Liverpool, United Kingdom, Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, L69 3GL, Liverpool, United Kingdom
⨯
Andrea L Jorgensen,

Affiliations MRC North West Hub For Trials Methodology Research, Liverpool, United Kingdom, Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, L69 3GL, Liverpool, United Kingdom
⨯
Ruwanthi Kolamunnage-Dona

Affiliations MRC North West Hub For Trials Methodology Research, Liverpool, United Kingdom, Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, L69 3GL, Liverpool, United Kingdom
⨯

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Biomarkers
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Phase II clinical investigation
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Clinical trials
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