Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

Laura M. Sanchez; Andrew T. Cheng; Christopher J. A. Warner; Loni Townsley; Kelly C. Peach; Gabriel Navarro; Nicholas J. Shikuma; Walter M. Bray; Romina M. Riener; Fitnat H. Yildiz; Roger G. Linington

doi:10.1371/journal.pone.0149603

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Open Access

Peer-reviewed

Research Article

Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

Laura M. Sanchez ,

Contributed equally to this work with: Laura M. Sanchez, Andrew T. Cheng, Christopher J. A. Warner

Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Andrew T. Cheng ,

Contributed equally to this work with: Laura M. Sanchez, Andrew T. Cheng, Christopher J. A. Warner

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Christopher J. A. Warner ,

Contributed equally to this work with: Laura M. Sanchez, Andrew T. Cheng, Christopher J. A. Warner

Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Loni Townsley,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Kelly C. Peach,

Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Gabriel Navarro,

Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Nicholas J. Shikuma,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Walter M. Bray,

Affiliation Chemical Screening Center, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Romina M. Riener,

Affiliation Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Fitnat H. Yildiz,

Affiliation Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America
⨯
Roger G. Linington

* E-mail: rliningt@sfu.ca

Affiliations Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, CA 95064, United States of America, Department of Chemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada
⨯

Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids

Laura M. Sanchez,
Andrew T. Cheng,
Christopher J. A. Warner,
Loni Townsley,
Kelly C. Peach,
Gabriel Navarro,
Nicholas J. Shikuma,
Walter M. Bray,
Romina M. Riener,
Fitnat H. Yildiz

Published: March 18, 2016
https://doi.org/10.1371/journal.pone.0149603

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Bile
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Vibrio cholerae
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