Proglucagon Promoter Cre-Mediated AMPK Deletion in Mice Increases Circulating GLP-1 Levels and Oral Glucose Tolerance

Open Access

Peer-reviewed

Research Article

Sophie R. Sayers,

Affiliation Department of Cell Biology and Functional Genomics, Imperial College London, London, W12 ONN, United Kingdom
⨯
Frank Reimann,

Affiliation Wellcome Trust - MRC Institute of Metabolic Science, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, United Kingdom
⨯
Fiona M. Gribble,

Affiliation Wellcome Trust - MRC Institute of Metabolic Science, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, United Kingdom
⨯
Helen Parker,

Affiliation Wellcome Trust - MRC Institute of Metabolic Science, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, United Kingdom
⨯
Sagen Zac-Varghese,

Affiliation Department of Investigative Medicine, Imperial College London, London, W12 ONN, United Kingdom
⨯
Stephen R. Bloom,

Affiliation Department of Investigative Medicine, Imperial College London, London, W12 ONN, United Kingdom
⨯
Marc Foretz,

Affiliations INSERM, U1016, Institut Cochin, 75014 Paris, France, CNRS, UMR8104, 75014 Paris, France, Université Paris Descartes, Sorbonne Paris Cité, 75014 Paris, France
⨯
Benoit Viollet,

Affiliations INSERM, U1016, Institut Cochin, 75014 Paris, France, CNRS, UMR8104, 75014 Paris, France, Université Paris Descartes, Sorbonne Paris Cité, 75014 Paris, France
⨯
Guy A. Rutter

* E-mail: g.rutter@imperial.ac.uk

Affiliation Department of Cell Biology and Functional Genomics, Imperial College London, London, W12 ONN, United Kingdom
⨯

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Glucagon
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Insulin
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Secretion
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Oral glucose suppression test
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Glucose tolerance
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Glucose
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Blood plasma
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Gastrointestinal tract
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