Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence

• Baasanjav Uranbileg,

  Affiliation Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan

  ⨯
• Hitoshi Ikeda ,

  * E-mail: ikeda-1im@h.u-tokyo.ac.jp

  Affiliations Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan, CREST, JST, Japan

  ⨯
• Makoto Kurano,

  Affiliations Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan, CREST, JST, Japan

  ⨯
• Kenichiro Enooku,

  Affiliation Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan

  ⨯
• Masaya Sato,

  Affiliation Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan

  ⨯
• Daisuke Saigusa,

  Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Miyagi, Japan, CREST, JST, Japan

  ⨯
• Junken Aoki,

  Affiliations Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi, Japan, CREST, JST, Japan

  ⨯
• Takeaki Ishizawa,

  Affiliation Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, The University of Tokyo, Tokyo, Japan

  ⨯
• Kiyoshi Hasegawa,

  Affiliation Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, The University of Tokyo, Tokyo, Japan

  ⨯
• Norihiro Kokudo,

  Affiliation Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, The University of Tokyo, Tokyo, Japan

  ⨯
• Yutaka Yatomi

  Affiliations Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan, CREST, JST, Japan

  ⨯