Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network

Andrea Tuettenberg; Susanne A. Hahn; Johanna Mazur; Aslihan Gerhold-Ay; Jetse Scholma; Iris Marg; Alexander Ulges; Kazuki Satoh; Tobias Bopp; Jos Joore; Helmut Jonuleit

doi:10.1371/journal.pone.0149193

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Open Access

Peer-reviewed

Research Article

Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network

Andrea Tuettenberg ,

* E-mail: andrea.tuettenberg@unimedizin-mainz.de

Affiliation Department of Dermatology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Susanne A. Hahn,

Affiliation Department of Dermatology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Johanna Mazur,

Affiliation Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Aslihan Gerhold-Ay,

Affiliation Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Jetse Scholma,

Affiliation Department of Developmental Bioengineering, University of Twente, Enschede, the Netherlands
⨯
Iris Marg,

Affiliation Department of Dermatology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Alexander Ulges,

Affiliation Institute for Immunology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Kazuki Satoh,

Affiliation Department of Dermatology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Tobias Bopp,

Affiliation Institute for Immunology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯
Jos Joore,

Affiliation Pepscope BV, Utrecht, The Netherlands
⨯
Helmut Jonuleit

Affiliation Department of Dermatology, University Medical Center Mainz, Johannes Gutenberg-University, Mainz, Germany
⨯

Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network

Andrea Tuettenberg,
Susanne A. Hahn,
Johanna Mazur,
Aslihan Gerhold-Ay,
Jetse Scholma,
Iris Marg,
Alexander Ulges,
Kazuki Satoh,
Tobias Bopp,
Jos Joore

Published: February 16, 2016
https://doi.org/10.1371/journal.pone.0149193

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Regulatory T cells
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T cells
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Phosphorylation
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Gene expression
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Protein kinases
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Flow cytometry
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Immune response
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