Genotypic Diversity of Staphylococcus aureus α-Hemolysin Gene (hla) and Its Association with Clonal Background: Implications for Vaccine Development

Meng Xiao; Rui Zhao; Qi Zhang; Xin Fan; Matthew V. N. O’Sullivan; Dong-Fang Li; Xin-Ying Wang; Hong-Long Wu; Fanrong Kong; Ying-Chun Xu

doi:10.1371/journal.pone.0149112

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Open Access

Peer-reviewed

Research Article

Genotypic Diversity of Staphylococcus aureus α-Hemolysin Gene (hla) and Its Association with Clonal Background: Implications for Vaccine Development

Meng Xiao ,

Contributed equally to this work with: Meng Xiao, Rui Zhao, Qi Zhang

Affiliation Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
⨯
Rui Zhao ,

Contributed equally to this work with: Meng Xiao, Rui Zhao, Qi Zhang

Affiliation Department of Laboratory, Beijing Electric Power Hospital, Beijing, China
⨯
Qi Zhang ,

Contributed equally to this work with: Meng Xiao, Rui Zhao, Qi Zhang

Affiliation Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
⨯
Xin Fan,

Affiliation Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
⨯
Matthew V. N. O’Sullivan,

Affiliations Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR – Pathology West, Westmead Hospital, University of Sydney, Westmead, New South Wales, Australia, Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney, New South Wales, Australia
⨯
Dong-Fang Li,

Affiliations Binhai Genomics Institute, BGI-Tianjin, BGI-shenzhen, Tianjin, China, Tianjin Translational Genomics Center, BGI-Tianjin, BGI-shenzhen, Tianjin, China
⨯
Xin-Ying Wang,

Affiliations Binhai Genomics Institute, BGI-Tianjin, BGI-shenzhen, Tianjin, China, Tianjin Translational Genomics Center, BGI-Tianjin, BGI-shenzhen, Tianjin, China
⨯
Hong-Long Wu,

Affiliations Binhai Genomics Institute, BGI-Tianjin, BGI-shenzhen, Tianjin, China, Tianjin Translational Genomics Center, BGI-Tianjin, BGI-shenzhen, Tianjin, China
⨯
Fanrong Kong,

Affiliation Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR – Pathology West, Westmead Hospital, University of Sydney, Westmead, New South Wales, Australia
⨯
Ying-Chun Xu

* E-mail: xycpumch@139.com

Affiliation Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
⨯

Genotypic Diversity of Staphylococcus aureus α-Hemolysin Gene (hla) and Its Association with Clonal Background: Implications for Vaccine Development

Meng Xiao,
Rui Zhao,
Qi Zhang,
Xin Fan,
Matthew V. N. O’Sullivan,
Dong-Fang Li,
Xin-Ying Wang,
Hong-Long Wu,
Fanrong Kong,
Ying-Chun Xu

Published: February 11, 2016
https://doi.org/10.1371/journal.pone.0149112

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