Metagenomic Sequencing of the Chronic Obstructive Pulmonary Disease Upper Bronchial Tract Microbiome Reveals Functional Changes Associated with Disease Severity

• Simon J. S. Cameron,

  Affiliation Institute of Biological, Environmental and Rural Sciences, Edward Llywd Building, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom

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• Keir E. Lewis,

  Affiliations Department of Respiratory Medicine, Prince Phillip Hospital, Hywel Dda University Health Board, Llanelli, SA14 8QF, United Kingdom, College of Medicine, Swansea University, Swansea, SA2 8PP, United Kingdom

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• Sharon A. Huws,

  Affiliation Institute of Biological, Environmental and Rural Sciences, Edward Llywd Building, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom

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• Wanchang Lin,

  Affiliation Institute of Biological, Environmental and Rural Sciences, Edward Llywd Building, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom

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• Matthew J. Hegarty,

  Affiliation Institute of Biological, Environmental and Rural Sciences, Edward Llywd Building, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom

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• Paul D. Lewis,

  Affiliation College of Medicine, Swansea University, Swansea, SA2 8PP, United Kingdom

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• Luis A. J. Mur ,

  * E-mail: lum@aber.ac.uk

  Affiliation Institute of Biological, Environmental and Rural Sciences, Edward Llywd Building, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom

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• Justin A. Pachebat

  Affiliation Institute of Biological, Environmental and Rural Sciences, Edward Llywd Building, Penglais Campus, Aberystwyth, Ceredigion, SY23 3FG, United Kingdom

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