Prefrontal Lobe Brain Reserve Capacity with Resistance to Higher Global Amyloid Load and White Matter Hyperintensity Burden in Mild Stage Alzheimer’s Disease

Ya-Ting Chang; Chi-Wei Huang; Nai-Ching Chen; Kun-Ju Lin; Shu-Hua Huang; Yen-Hsiang Chang; Shih-Wei Hsu; Wen-Neng Chang; Chun-Chung Lui; Che-Wei Hsu; Chiung-Chih Chang

doi:10.1371/journal.pone.0149056

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Open Access

Peer-reviewed

Research Article

Prefrontal Lobe Brain Reserve Capacity with Resistance to Higher Global Amyloid Load and White Matter Hyperintensity Burden in Mild Stage Alzheimer’s Disease

Ya-Ting Chang,

Affiliation Cognition and Aging Center, Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Chi-Wei Huang,

Affiliation Cognition and Aging Center, Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Nai-Ching Chen,

Affiliation Cognition and Aging Center, Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Kun-Ju Lin,

Affiliation Department of Nuclear Medicine and Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Taoyuan, Taiwan
⨯
Shu-Hua Huang,

Affiliation Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Yen-Hsiang Chang,

Affiliation Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Shih-Wei Hsu,

Affiliation Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Wen-Neng Chang,

Affiliation Cognition and Aging Center, Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Chun-Chung Lui,

Affiliation Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Che-Wei Hsu,

Affiliation Cognition and Aging Center, Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯
Chiung-Chih Chang

* E-mail: neur099@adm.cgmh.org.tw

Affiliation Cognition and Aging Center, Departments of Neurology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
⨯

Prefrontal Lobe Brain Reserve Capacity with Resistance to Higher Global Amyloid Load and White Matter Hyperintensity Burden in Mild Stage Alzheimer’s Disease

Ya-Ting Chang,
Chi-Wei Huang,
Nai-Ching Chen,
Kun-Ju Lin,
Shu-Hua Huang,
Yen-Hsiang Chang,
Shih-Wei Hsu,
Wen-Neng Chang,
Chun-Chung Lui,
Che-Wei Hsu

Published: February 12, 2016
https://doi.org/10.1371/journal.pone.0149056

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