Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways

Zhao Gao; Yu Han; Yunhui Hu; Xiaoyan Wu; Yongbin Wang; Xiaoqun Zhang; Jinjuan Fu; Xue Zou; Jun Zhang; Xiongwen Chen; Pedro A. Jose; Xi Lu; Chunyu Zeng

doi:10.1371/journal.pone.0149032

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Research Article

Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways

Zhao Gao ,

Contributed equally to this work with: Zhao Gao, Yu Han

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Yu Han ,

Contributed equally to this work with: Zhao Gao, Yu Han

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Yunhui Hu,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Xiaoyan Wu,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Yongbin Wang,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Xiaoqun Zhang,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Jinjuan Fu,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Xue Zou,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Jun Zhang,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Xiongwen Chen,

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Pedro A. Jose,

Affiliations Department of Medicine, Division of Renal Disease and Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, United States of America, Department of Physiology, The George Washington University School of Medicine & Health Sciences, Washington, DC, United States of America
⨯
Xi Lu ,

* E-mail: chunyuzeng01@163.com (CZ); xixi0332@126.com (XL)

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯
Chunyu Zeng

* E-mail: chunyuzeng01@163.com (CZ); xixi0332@126.com (XL)

Affiliations Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China, Chongqing Institute of Cardiology, Chongqing Key Laboratory for Hypertension Research, Chongqing, P.R. China
⨯

Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways

Zhao Gao,
Yu Han,
Yunhui Hu,
Xiaoyan Wu,
Yongbin Wang,
Xiaoqun Zhang,
Jinjuan Fu,
Xue Zou,
Jun Zhang,
Xiongwen Chen

Published: February 11, 2016
https://doi.org/10.1371/journal.pone.0149032

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