AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

Astra Dinculescu; Rachel M. Stupay; Wen-Tao Deng; Frank M. Dyka; Seok-Hong Min; Sanford L. Boye; Vince A. Chiodo; Carolina E. Abrahan; Ping Zhu; Qiuhong Li; Enrica Strettoi; Elena Novelli; Kerstin Nagel-Wolfrum; Uwe Wolfrum; W. Clay Smith; William W. Hauswirth

doi:10.1371/journal.pone.0148874

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Open Access

Peer-reviewed

Research Article

AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

Astra Dinculescu ,

Contributed equally to this work with: Astra Dinculescu, Rachel M. Stupay

* E-mail: astra@ufl.edu

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Rachel M. Stupay ,

Contributed equally to this work with: Astra Dinculescu, Rachel M. Stupay

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Wen-Tao Deng,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Frank M. Dyka,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Seok-Hong Min,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Sanford L. Boye,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Vince A. Chiodo,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Carolina E. Abrahan,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Ping Zhu,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Qiuhong Li,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
Enrica Strettoi,

Affiliation CNR Neuroscience Institute, Pisa, Italy
⨯
Elena Novelli,

Affiliation CNR Neuroscience Institute, Pisa, Italy
⨯
Kerstin Nagel-Wolfrum,

Affiliation Cell and Matrix Biology, Institute of Zoology, Johannes Gutenberg-University of Mainz, Mainz, Germany
⨯
Uwe Wolfrum,

Affiliation Cell and Matrix Biology, Institute of Zoology, Johannes Gutenberg-University of Mainz, Mainz, Germany
⨯
W. Clay Smith,

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
[ ... ],
William W. Hauswirth

Affiliation Ophthalmology, University of Florida, Gainesville, FL, United States of America
⨯
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AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy

Astra Dinculescu,
Rachel M. Stupay,
Wen-Tao Deng,
Frank M. Dyka,
Seok-Hong Min,
Sanford L. Boye,
Vince A. Chiodo,
Carolina E. Abrahan,
Ping Zhu,
Qiuhong Li

Published: February 16, 2016
https://doi.org/10.1371/journal.pone.0148874

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