Impact of Reducing Complement Inhibitor Binding on the Immunogenicity of Native Neisseria meningitidis Outer Membrane Vesicles

• Helene Daniels-Treffandier,

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯
• Karlijn de Nie,

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯
• Leanne Marsay,

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯
• Christina Dold,

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯
• Manish Sadarangani,

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯
• Arturo Reyes-Sandoval,

  Affiliation The Jenner Institute, University of Oxford, Centre for Cellular and Molecular Physiology, The Henry Wellcome Building for Molecular Physiology, Roosevelt Drive, Oxford, OX3 7BN, United Kingdom

  ⨯
• Paul R. Langford,

  Affiliation Section of Paediatrics, St Mary’s Campus, Imperial College, London, W2 1PG, United Kingdom

  ⨯
• David Wyllie,

  Affiliation The Jenner Institute, University of Oxford, Centre for Cellular and Molecular Physiology, The Henry Wellcome Building for Molecular Physiology, Roosevelt Drive, Oxford, OX3 7BN, United Kingdom

  ⨯
• Fergal Hill,

  Affiliation Imaxio, 99 rue de Gerland, 69007, Lyon, France

  ⨯
• Andrew J. Pollard,

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯
• Christine S. Rollier

  * E-mail: christine.rollier@paediatrics.ox.ac.uk

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and The NIHR Oxford Biomedical Research Centre, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, OX3 7LE, United Kingdom

  ⨯