High-Dose Fluoride Impairs the Properties of Human Embryonic Stem Cells via JNK Signaling

Open Access

Peer-reviewed

Research Article

Xin Fu,

Affiliation Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Ba Da Chu Road, Beijing, 100144, PR China
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Fang-Nan Xie,

Affiliation Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Ba Da Chu Road, Beijing, 100144, PR China
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Ping Dong,

Affiliation Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Ba Da Chu Road, Beijing, 100144, PR China
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Qiu-Chen Li,

Affiliation Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Ba Da Chu Road, Beijing, 100144, PR China
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Guang-Yan Yu,

Affiliation Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology, 22 Zhong Guan Cun South St., Beijing, 100081, PR China
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Ran Xiao

* E-mail: xiaoran@psh.pumc.edu.cn

Affiliation Research Center of Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Ba Da Chu Road, Beijing, 100144, PR China
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Apoptosis
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Fluorides
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Cell differentiation
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Embryogenesis
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c-Jun N-terminal kinase signaling cascade
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Gene expression
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Mitochondria
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Reactive oxygen species
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