Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells

Open Access

Peer-reviewed

Research Article

Chung-Weng Phang,

Affiliation Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
⨯
Saiful Anuar Karsani,

Affiliation Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
⨯
Gautam Sethi,

Affiliation Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore, Singapore
⨯
Sri Nurestri Abd Malek

* E-mail: srimalek@um.edu.my

Affiliation Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
⨯

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Apoptosis
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Mitochondria
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Cell cycle and cell division
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Colorectal cancer
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AKT signaling cascade
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Endoplasmic reticulum
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Flow cytometry
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Synthesis phase
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