Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

James D. West; Erica J. Carrier; Nathaniel C. Bloodworth; Alison K. Schroer; Peter Chen; Larisa M. Ryzhova; Santhi Gladson; Sheila Shay; Joshua D. Hutcheson; W. David Merryman

doi:10.1371/journal.pone.0148657

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Open Access

Peer-reviewed

Research Article

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

James D. West ,

Contributed equally to this work with: James D. West, Erica J. Carrier, Nathaniel C. Bloodworth

* E-mail: j.west@vanderbilt.edu (JDW); david.merryman@vanderbilt.edu (WDM)

Affiliation Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States of America
⨯
Erica J. Carrier ,

Contributed equally to this work with: James D. West, Erica J. Carrier, Nathaniel C. Bloodworth

Affiliation Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States of America
⨯
Nathaniel C. Bloodworth ,

Contributed equally to this work with: James D. West, Erica J. Carrier, Nathaniel C. Bloodworth

Affiliation Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, 37232, United States of America
⨯
Alison K. Schroer,

Affiliation Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, 37232, United States of America
⨯
Peter Chen,

Affiliation Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States of America
⨯
Larisa M. Ryzhova,

Affiliation Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, 37232, United States of America
⨯
Santhi Gladson,

Affiliation Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States of America
⨯
Sheila Shay,

Affiliation Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States of America
⨯
Joshua D. Hutcheson,

Affiliation Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, 37232, United States of America
⨯
W. David Merryman

* E-mail: j.west@vanderbilt.edu (JDW); david.merryman@vanderbilt.edu (WDM)

Affiliation Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, 37232, United States of America
⨯

Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension

James D. West,
Erica J. Carrier,
Nathaniel C. Bloodworth,
Alison K. Schroer,
Peter Chen,
Larisa M. Ryzhova,
Santhi Gladson,
Sheila Shay,
Joshua D. Hutcheson,
W. David Merryman

Published: February 10, 2016
https://doi.org/10.1371/journal.pone.0148657

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