Down-Regulation of Surface CD28 under Belatacept Treatment: An Escape Mechanism for Antigen-Reactive T-Cells

Open Access

Peer-reviewed

Research Article

Gretchen N. de Graav ,

* E-mail: g.degraav@erasmusmc.nl

Affiliation Department of Internal Medicine, Section of Transplantation and Nephrology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
⨯
Dennis A. Hesselink,

Affiliation Department of Internal Medicine, Section of Transplantation and Nephrology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
⨯
Marjolein Dieterich,

Affiliation Department of Internal Medicine, Section of Transplantation and Nephrology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
⨯
Rens Kraaijeveld,

Affiliation Department of Internal Medicine, Section of Transplantation and Nephrology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
⨯
Willem Weimar,

Affiliation Department of Internal Medicine, Section of Transplantation and Nephrology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
⨯
Carla C. Baan

Affiliation Department of Internal Medicine, Section of Transplantation and Nephrology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
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T cells
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Cytotoxic T cells
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Cell differentiation
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Renal transplantation
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Chronic kidney disease
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Antigen-presenting cells
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Cell staining
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Signal inhibition
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