Automated Protein Localization of Blood Brain Barrier Vasculature in Brightfield IHC Images

Open Access

Peer-reviewed

Research Article

Rajath E. Soans ,

Contributed equally to this work with: Rajath E. Soans, Diane C. Lim

Affiliation Department of Electrical Engineering, Drexel University, Philadelphia, United States of America
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Diane C. Lim ,

Contributed equally to this work with: Rajath E. Soans, Diane C. Lim

Affiliation Department of Medicine, University of Pennsylvania, Philadelphia, United States of America
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Brendan T. Keenan,

Affiliation Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, United States of America
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Allan I. Pack,

Affiliation Department of Medicine, University of Pennsylvania, Philadelphia, United States of America
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James A. Shackleford

* E-mail: shack@drexel.edu

Affiliation Department of Electrical Engineering, Drexel University, Philadelphia, United States of America
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Entropy
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Hippocampus
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Immunohistochemistry techniques
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Blood-brain barrier
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Bright field microscopy
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Imaging techniques
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Algorithms
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k means clustering
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