A Computational Cognitive Biomarker for Early-Stage Huntington’s Disease

• Thomas V. Wiecki,

  Affiliation Cognitive, Linguistic & Psychological Sciences, Brown, Providence, United States of America

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• Chrystalina A. Antoniades,

  Affiliation Division of Clinical Neurology, Nuffield Department of Clinical Neurosciences, Level 6 West Wing, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, United Kingdom

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• Alexander Stevenson,

  Affiliation Division of Clinical Neurology, Nuffield Department of Clinical Neurosciences, Level 6 West Wing, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, United Kingdom

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• Christopher Kennard,

  Affiliation Division of Clinical Neurology, Nuffield Department of Clinical Neurosciences, Level 6 West Wing, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, United Kingdom

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• Beth Borowsky,

  Affiliation CHDI Management Inc/CHDI Foundation, 155 Village Boulevard, Suite 200, Princeton, NJ 08540, United States of America

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• Gail Owen,

  Affiliation Huntington’s Disease Research Centre, UCL Institute of Neurology, 2nd Floor Russell Square House, 10-12 Russell Square, London, WC1B 5EH, United Kingdom

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• Blair Leavitt,

  Affiliation Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada

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• Raymund Roos,

  Affiliation Department of Neurology, Leiden University Medical Centre, 2300RC Leiden, The Netherlands

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• Alexandra Durr,

  Affiliation Department of Genetics and Cytogenetics, and INSERM UMR S679, APHP Hôpital de la Salpêtrière, 75013 Paris, France

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• Sarah J. Tabrizi,

  Affiliation Huntington’s Disease Research Centre, UCL Institute of Neurology, 2nd Floor Russell Square House, 10-12 Russell Square, London, WC1B 5EH, United Kingdom

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• Michael J. Frank

  * E-mail: michael_frank@brown.edu

  Affiliation Cognitive, Linguistic & Psychological Sciences, Brown, Providence, United States of America

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