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Open Access

Peer-reviewed

Research Article

Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling

Zhekang Ying ,

* E-mail: yingzhekang@hotmail.com

Affiliations Department of Cardiology, East Hospital, Tongji University School of Medicine, Shanghai, 200120, PR China, Department of Medicine Cardiology Division, University of Maryland School of Medicine, Baltimore, Maryland, 21201, United States of America
⨯
Minjie Chen,

Affiliations Department of Cardiology, East Hospital, Tongji University School of Medicine, Shanghai, 200120, PR China, Department of Medicine Cardiology Division, University of Maryland School of Medicine, Baltimore, Maryland, 21201, United States of America
⨯
Xiaoyun Xie,

Affiliations Davis Heart & Lung Research Institute, Colleges of Medicine, The Ohio State University, Columbus, Ohio, United States of America, Division of Geriatric Medicine, Tongji Hospital, Tongji University School of Medicine, Shanghai, PR China
⨯
Xiaoke Wang,

Affiliation Department of Medicine Cardiology Division, University of Maryland School of Medicine, Baltimore, Maryland, 21201, United States of America
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Nisharahmed Kherada,

Affiliation Davis Heart & Lung Research Institute, Colleges of Medicine, The Ohio State University, Columbus, Ohio, United States of America
⨯
Rajagopal Desikan,

Current address: Department of chemistry and pharmaceutical chemistry, School of Advanced Science, VIT University, Vellore, 632014, India

Affiliations Davis Heart & Lung Research Institute, Colleges of Medicine, The Ohio State University, Columbus, Ohio, United States of America, InVasc Therapeutics, Tucker, Georgia, United States of America
⨯
Georgeta Mihai,

Affiliation Davis Heart & Lung Research Institute, Colleges of Medicine, The Ohio State University, Columbus, Ohio, United States of America
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Patrick Burns,

Affiliation Davis Heart & Lung Research Institute, Colleges of Medicine, The Ohio State University, Columbus, Ohio, United States of America
⨯
Qinghua Sun,

Affiliation Davis Heart & Lung Research Institute, Colleges of Medicine, The Ohio State University, Columbus, Ohio, United States of America
⨯
Sanjay Rajagopalan

Affiliation Department of Medicine Cardiology Division, University of Maryland School of Medicine, Baltimore, Maryland, 21201, United States of America
⨯

Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling

Zhekang Ying,
Minjie Chen,
Xiaoyun Xie,
Xiaoke Wang,
Nisharahmed Kherada,
Rajagopal Desikan,
Georgeta Mihai,
Patrick Burns,
Qinghua Sun,
Sanjay Rajagopalan

x

Published: February 9, 2016
https://doi.org/10.1371/journal.pone.0148305

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Atherosclerosis
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Aorta
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Magnetic resonance imaging
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Rabbits
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Chemotaxis
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White blood cells
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Macrophages
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Lipoic acids
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